The AV valves are located at the base of each ventricle in your heart. They help to regulate blood flow and pressure by opening when they receive a signal from your heart’s electrical system, allowing for more blood to be pumped through the body with every beat. Remember that these valves only open during systole (the contraction phase) and close as soon as it ends, which prevents backflow of blood into either ventricle or aneurysmal dilatation (widening).